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The involvement of AIFM2 in ferroptosis is influenced by phase separation, a process in which a homogeneous mixture of substances spontaneously separates into distinct phases, and can be initiated through N-terminal myristoylation, which is facilitated by a compound called icFSP1 in a variety of human cancer cells [14]
IP3 may potentially trigger the release of calcium ions (Ca2+) from intracellular stores, while DAG potentially activates protein kinase C (PKC)
the weight loss was -9.24 0.007% on the 4th day (Fig
They also have a boxed warning regarding thyroid C-cell tumors observed in rodents (though human relevance remains uncertain)
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